LY-364947,HTS 466284
>98%
- Product Code: 101331
CAS:
396129-53-6
| Molecular Weight: | 272.3 g./mol | Molecular Formula: | C₁₇H₁₂N₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
LY-364947, also known as HTS 466284, is primarily used in research settings as a selective inhibitor of the transforming growth factor-beta (TGF-β) type I receptor, also known as ALK5. Its application is significant in the study of cellular processes and signaling pathways influenced by TGF-β, which plays a crucial role in various biological functions such as cell proliferation, differentiation, and apoptosis. Researchers utilize this compound to investigate the effects of TGF-β signaling in diseases like fibrosis, cancer, and autoimmune disorders. By inhibiting ALK5, LY-364947 helps elucidate the therapeutic potential of targeting TGF-β pathways in these conditions. Additionally, it serves as a valuable tool in drug discovery and development, aiding in the identification of novel treatments for TGF-β-related pathologies.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Yellow Powder |
| Purity (%) | 98-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $152.58 |
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| 0.010 | 10-20 days | $247.36 |
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| 0.050 | 10-20 days | $1,057.87 |
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LY-364947,HTS 466284
LY-364947, also known as HTS 466284, is primarily used in research settings as a selective inhibitor of the transforming growth factor-beta (TGF-β) type I receptor, also known as ALK5. Its application is significant in the study of cellular processes and signaling pathways influenced by TGF-β, which plays a crucial role in various biological functions such as cell proliferation, differentiation, and apoptosis. Researchers utilize this compound to investigate the effects of TGF-β signaling in diseases like fibrosis, cancer, and autoimmune disorders. By inhibiting ALK5, LY-364947 helps elucidate the therapeutic potential of targeting TGF-β pathways in these conditions. Additionally, it serves as a valuable tool in drug discovery and development, aiding in the identification of novel treatments for TGF-β-related pathologies.
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