MI-2
≥98%
- Product Code: 101386
CAS:
1271738-62-5
| Molecular Weight: | 375.55 g./mol | Molecular Formula: | C₁₈H₂₅N₅S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
MI-2 is primarily utilized in research settings to study its interaction with the NOTCH signaling pathway, which plays a crucial role in cellular differentiation, proliferation, and apoptosis. It is particularly investigated for its potential to inhibit the activity of the MAML1 protein, a key coactivator in the NOTCH pathway. This inhibition is of significant interest in cancer research, as aberrant NOTCH signaling is implicated in various malignancies. By targeting this pathway, MI-2 serves as a tool to explore therapeutic strategies for cancers where NOTCH signaling is dysregulated, such as T-cell acute lymphoblastic leukemia (T-ALL) and other NOTCH-dependent tumors. Additionally, it aids in understanding the broader biological mechanisms influenced by NOTCH signaling in both normal and pathological conditions.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Yellow Solid |
| Purity (%) | 98-100 |
| Nmr | Consistent With Structure |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿8,982.00 |
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| 0.025 | 10-20 days | ฿32,436.00 |
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| 0.100 | 10-20 days | ฿64,881.00 |
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MI-2
MI-2 is primarily utilized in research settings to study its interaction with the NOTCH signaling pathway, which plays a crucial role in cellular differentiation, proliferation, and apoptosis. It is particularly investigated for its potential to inhibit the activity of the MAML1 protein, a key coactivator in the NOTCH pathway. This inhibition is of significant interest in cancer research, as aberrant NOTCH signaling is implicated in various malignancies. By targeting this pathway, MI-2 serves as a tool to explore therapeutic strategies for cancers where NOTCH signaling is dysregulated, such as T-cell acute lymphoblastic leukemia (T-ALL) and other NOTCH-dependent tumors. Additionally, it aids in understanding the broader biological mechanisms influenced by NOTCH signaling in both normal and pathological conditions.
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| Stable in pH range | - |
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