PF-915275
≥98%
- Product Code: 101972
CAS:
857290-04-1
| Molecular Weight: | 350.39 g./mol | Molecular Formula: | C₁₈H₁₄N₄O₂S |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
PF-915275 is primarily utilized in research settings as a potent and selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This enzyme plays a crucial role in the regulation of cortisol levels within tissues, and its inhibition is of significant interest in the study of metabolic disorders. By blocking 11β-HSD1, PF-915275 helps reduce local cortisol production, which is beneficial in investigating conditions such as obesity, type 2 diabetes, and metabolic syndrome. Its application extends to preclinical studies aimed at understanding the role of cortisol in insulin resistance and glucose metabolism. Additionally, it serves as a valuable tool in pharmacological research to explore the therapeutic potential of 11β-HSD1 inhibitors in managing these metabolic diseases.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿9,234.00 |
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| 0.010 | 10-20 days | ฿12,312.00 |
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PF-915275
PF-915275 is primarily utilized in research settings as a potent and selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This enzyme plays a crucial role in the regulation of cortisol levels within tissues, and its inhibition is of significant interest in the study of metabolic disorders. By blocking 11β-HSD1, PF-915275 helps reduce local cortisol production, which is beneficial in investigating conditions such as obesity, type 2 diabetes, and metabolic syndrome. Its application extends to preclinical studies aimed at understanding the role of cortisol in insulin resistance and glucose metabolism. Additionally, it serves as a valuable tool in pharmacological research to explore the therapeutic potential of 11β-HSD1 inhibitors in managing these metabolic diseases.
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