PX-12
99%
- Product Code: 102184
CAS:
141400-58-0
| Molecular Weight: | 188.31 g./mol | Molecular Formula: | C₇H₁₂N₂S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18086851 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
PX-12 is primarily investigated for its potential applications in cancer therapy. It functions as an inhibitor of thioredoxin-1 (Trx-1), a protein that plays a crucial role in cancer cell survival and proliferation. By inhibiting Trx-1, PX-12 disrupts the redox balance within cancer cells, leading to increased oxidative stress and ultimately inducing cell death. This mechanism makes it a promising candidate for targeting various types of cancers, particularly those that are resistant to conventional treatments. Additionally, PX-12 has shown potential in reducing tumor growth in preclinical studies, making it a subject of interest for further clinical development. Its ability to enhance the efficacy of other anticancer therapies when used in combination is also being explored.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Solid |
| Purity (%) | 98.5-100 |
| Proton Nmr Spectrum | Conforms To Structure |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿2,980.00 |
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| 0.025 | 10-20 days | ฿9,170.00 |
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| 0.100 | 10-20 days | ฿24,120.00 |
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PX-12
PX-12 is primarily investigated for its potential applications in cancer therapy. It functions as an inhibitor of thioredoxin-1 (Trx-1), a protein that plays a crucial role in cancer cell survival and proliferation. By inhibiting Trx-1, PX-12 disrupts the redox balance within cancer cells, leading to increased oxidative stress and ultimately inducing cell death. This mechanism makes it a promising candidate for targeting various types of cancers, particularly those that are resistant to conventional treatments. Additionally, PX-12 has shown potential in reducing tumor growth in preclinical studies, making it a subject of interest for further clinical development. Its ability to enhance the efficacy of other anticancer therapies when used in combination is also being explored.
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