RAF709
99%
- Product Code: 102249
CAS:
1628838-42-5
| Molecular Weight: | 542.55 g./mol | Molecular Formula: | C₂₈H₂₉F₃N₄O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD30534393 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
RAF709 is primarily utilized in the field of medical research, particularly in the study of cancer therapies. It functions as a potent and selective inhibitor of the RAF kinase enzyme, which plays a critical role in the MAPK/ERK signaling pathway. This pathway is often dysregulated in various cancers, leading to uncontrolled cell proliferation and survival.
In preclinical studies, RAF709 has been employed to investigate its potential in inhibiting tumor growth, especially in cancers driven by mutations in the BRAF gene, such as melanoma, colorectal cancer, and thyroid cancer. Its selectivity allows researchers to target specific components of the signaling pathway, minimizing off-target effects and providing insights into the mechanisms of RAF-dependent cancers.
Additionally, RAF709 is used in drug development to explore combination therapies, where it may enhance the efficacy of other anticancer agents. Its role in understanding resistance mechanisms to RAF inhibitors is also significant, aiding in the design of more effective treatment strategies for patients with refractory cancers.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿8,892.00 |
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RAF709
RAF709 is primarily utilized in the field of medical research, particularly in the study of cancer therapies. It functions as a potent and selective inhibitor of the RAF kinase enzyme, which plays a critical role in the MAPK/ERK signaling pathway. This pathway is often dysregulated in various cancers, leading to uncontrolled cell proliferation and survival.
In preclinical studies, RAF709 has been employed to investigate its potential in inhibiting tumor growth, especially in cancers driven by mutations in the BRAF gene, such as melanoma, colorectal cancer, and thyroid cancer. Its selectivity allows researchers to target specific components of the signaling pathway, minimizing off-target effects and providing insights into the mechanisms of RAF-dependent cancers.
Additionally, RAF709 is used in drug development to explore combination therapies, where it may enhance the efficacy of other anticancer agents. Its role in understanding resistance mechanisms to RAF inhibitors is also significant, aiding in the design of more effective treatment strategies for patients with refractory cancers.
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