tBID
≥98%
- Product Code: 102813
CAS:
1639895-85-4
| Molecular Weight: | 528.78 g./mol | Molecular Formula: | C₁₁H₃Br₄N₃O₂ |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
tBID is a truncated form of the BID protein, which plays a critical role in the intrinsic pathway of apoptosis, or programmed cell death. It is generated through cleavage by caspase-8 and acts as a potent pro-apoptotic signal. tBID translocates to the mitochondria, where it interacts with other BCL-2 family proteins, such as BAX and BAK, to induce mitochondrial outer membrane permeabilization (MOMP). This process leads to the release of cytochrome c and other apoptogenic factors, triggering the activation of downstream caspases and ultimately resulting in cell death. Due to its role in apoptosis, tBID is studied in cancer research to understand mechanisms of tumor suppression and resistance to cell death. It is also explored in the context of neurodegenerative diseases, where dysregulation of apoptosis contributes to neuronal loss. Additionally, tBID is used as a tool in biochemical studies to investigate mitochondrial function and the regulation of cell death pathways.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿15,390.00 |
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| 0.005 | 10-20 days | ฿35,910.00 |
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tBID
tBID is a truncated form of the BID protein, which plays a critical role in the intrinsic pathway of apoptosis, or programmed cell death. It is generated through cleavage by caspase-8 and acts as a potent pro-apoptotic signal. tBID translocates to the mitochondria, where it interacts with other BCL-2 family proteins, such as BAX and BAK, to induce mitochondrial outer membrane permeabilization (MOMP). This process leads to the release of cytochrome c and other apoptogenic factors, triggering the activation of downstream caspases and ultimately resulting in cell death. Due to its role in apoptosis, tBID is studied in cancer research to understand mechanisms of tumor suppression and resistance to cell death. It is also explored in the context of neurodegenerative diseases, where dysregulation of apoptosis contributes to neuronal loss. Additionally, tBID is used as a tool in biochemical studies to investigate mitochondrial function and the regulation of cell death pathways.
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