TH588
>98%
- Product Code: 102904
CAS:
1609960-31-7
| Molecular Weight: | 295.17 g./mol | Molecular Formula: | C₁₃H₁₂Cl₂N₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
TH588 is primarily investigated for its potential applications in cancer research due to its ability to selectively target and inhibit MTH1, an enzyme that plays a role in DNA repair mechanisms. By disrupting MTH1, it induces oxidative DNA damage in cancer cells, leading to their death while sparing healthy cells. This makes it a promising candidate for developing targeted cancer therapies. Additionally, it is studied for its effects on neurodegenerative diseases, as oxidative stress is a key factor in conditions like Alzheimer's and Parkinson’s. Researchers are exploring its utility in understanding cellular mechanisms and developing treatments for these diseases.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White Solid |
| Purity (%) | 100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | Ft42,126.76 |
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| 0.025 | 10-20 days | Ft144,373.05 |
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TH588
TH588 is primarily investigated for its potential applications in cancer research due to its ability to selectively target and inhibit MTH1, an enzyme that plays a role in DNA repair mechanisms. By disrupting MTH1, it induces oxidative DNA damage in cancer cells, leading to their death while sparing healthy cells. This makes it a promising candidate for developing targeted cancer therapies. Additionally, it is studied for its effects on neurodegenerative diseases, as oxidative stress is a key factor in conditions like Alzheimer's and Parkinson’s. Researchers are exploring its utility in understanding cellular mechanisms and developing treatments for these diseases.
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| Stable in pH range | - |
| Solubility | - |
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| INCI | - |
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