Fmoc-His(Boc)-OH
95%
- Product Code: 104413
Alias:
FMOC-BOC-histidine, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluorene-9-methoxy)carbonyl]-l-histidine
CAS:
81379-52-4
| Molecular Weight: | 477.51 g./mol | Molecular Formula: | C₂₆H₂₇N₃O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00151928 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.32 g/cm3 | Storage Condition: | 2-8°C |
Product Description:
Fmoc-His(Boc)-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of histidine, where the Fmoc group protects the amino group and the Boc group protects the imidazole side chain. This protection ensures selective deprotection during the synthesis process, allowing for the controlled assembly of peptides. It is especially valuable in synthesizing peptides containing histidine residues, which are crucial for biological activity in many proteins and peptides. Its application extends to the production of therapeutic peptides, research peptides, and peptide-based drugs, where precise sequence control is essential. Additionally, it is used in the development of peptide libraries for drug discovery and biochemical studies.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White Solid |
| Purity (%) | 94.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | Ft4,309.64 |
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| 1.000 | 10-20 days | Ft7,110.91 |
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| 5.000 | 10-20 days | Ft26,719.79 |
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| 25.000 | 10-20 days | Ft127,134.47 |
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Fmoc-His(Boc)-OH
Fmoc-His(Boc)-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of histidine, where the Fmoc group protects the amino group and the Boc group protects the imidazole side chain. This protection ensures selective deprotection during the synthesis process, allowing for the controlled assembly of peptides. It is especially valuable in synthesizing peptides containing histidine residues, which are crucial for biological activity in many proteins and peptides. Its application extends to the production of therapeutic peptides, research peptides, and peptide-based drugs, where precise sequence control is essential. Additionally, it is used in the development of peptide libraries for drug discovery and biochemical studies.
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