Fmoc-α-Me-Ala-OH
97%
- Product Code: 104998
Alias:
Fmoc-2-aminoisobutyric acid; N-fluorenylmethoxycarbonyl-2-aminoisobutyric acid
CAS:
94744-50-0
| Molecular Weight: | 325.36 g./mol | Molecular Formula: | C₁₉H₁₉NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00151913 | |
| Melting Point: | 182-188 °C | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
Fmoc-α-Me-Ala-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality. This allows for the sequential assembly of peptides by selectively deprotecting and coupling amino acids. The α-methyl group introduces steric hindrance, which can influence the peptide's conformation and stability, making it valuable in the design of peptidomimetics and bioactive peptides. Its application is crucial in pharmaceutical research, where it aids in the development of peptide-based drugs, enzyme inhibitors, and probes for studying protein interactions. Additionally, it is utilized in the synthesis of modified peptides for structural and functional studies in biochemistry and molecular biology.
Product Specification:
| Test | Specification |
|---|---|
| Melting Point | 182-188 |
| Purity (HPLC) | 97-100 |
| Appearance | White To Almost White Powder To Crystal |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 5.000 | 10-20 days | ฿720.00 |
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| 25.000 | 10-20 days | ฿1,640.00 |
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| 100.000 | 10-20 days | ฿5,400.00 |
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Fmoc-α-Me-Ala-OH
Fmoc-α-Me-Ala-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality. This allows for the sequential assembly of peptides by selectively deprotecting and coupling amino acids. The α-methyl group introduces steric hindrance, which can influence the peptide's conformation and stability, making it valuable in the design of peptidomimetics and bioactive peptides. Its application is crucial in pharmaceutical research, where it aids in the development of peptide-based drugs, enzyme inhibitors, and probes for studying protein interactions. Additionally, it is utilized in the synthesis of modified peptides for structural and functional studies in biochemistry and molecular biology.
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