Fmoc-Ser(tBu)-OH
98%
- Product Code: 105135
Alias:
FMOC-O-tert-butyl-L-serine ; N-(9-fluorenylmethoxycarbonyl)-O-tert-butyl-L-serine
CAS:
71989-33-8
Molecular Weight: | 383.44 g./mol | Molecular Formula: | C₂₂H₂₅NO₅ |
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EC Number: | 276-260-6 | MDL Number: | MFCD00037127 |
Melting Point: | 130.5-135.5 °C(lit.) | Boiling Point: | |
Density: | Storage Condition: | 2~8°C |
Product Description:
Fmoc-Ser(tBu)-OH is widely used in solid-phase peptide synthesis (SPPS) as a building block for creating peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) group protects the amino group during synthesis, while the tBu (tert-butyl) group shields the hydroxyl group of serine, preventing unwanted side reactions. This compound is particularly valuable in synthesizing complex peptides and proteins, ensuring high purity and yield. It is also employed in the development of peptide-based drugs, biomaterials, and research tools for studying biological processes. Its stability and compatibility with standard SPPS protocols make it a preferred choice in peptide chemistry.
Product Specification:
Test | Specification |
---|---|
Purity (HPLC) | 98-100 |
Specific Rotation [A]20/D(C=1% In Ethyl Acetate) | 24.5-26.5 |
Specific Rotation [A]20/D(C=1% In Ethyl Acetate) | 24.5 26.5° |
Appearance | White Powder |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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5.000 | 10-20 days | ฿400.00 |
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25.000 | 10-20 days | ฿1,880.00 |
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100.000 | 10-20 days | ฿6,890.00 |
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Fmoc-Ser(tBu)-OH
Fmoc-Ser(tBu)-OH is widely used in solid-phase peptide synthesis (SPPS) as a building block for creating peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) group protects the amino group during synthesis, while the tBu (tert-butyl) group shields the hydroxyl group of serine, preventing unwanted side reactions. This compound is particularly valuable in synthesizing complex peptides and proteins, ensuring high purity and yield. It is also employed in the development of peptide-based drugs, biomaterials, and research tools for studying biological processes. Its stability and compatibility with standard SPPS protocols make it a preferred choice in peptide chemistry.
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