Fmoc-Cysteinol(acm)
98%
- Product Code: 105152
CAS:
198543-46-3
| Molecular Weight: | 400.49 g./mol | Molecular Formula: | C₂₁H₂₄N₂O₄S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD02094116 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, sealed, dry |
Product Description:
Fmoc-Cysteinol(acm) is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of cysteinol, where the Fmoc group protects the amino functionality, and the acm (acetamidomethyl) group protects the thiol functionality of the cysteine residue. This protection is crucial to prevent unwanted side reactions during the synthesis process. After the peptide chain is assembled, the Fmoc group can be removed under mild basic conditions, while the acm group can be selectively removed later using specific reagents like iodine or silver salts. This allows for the controlled formation of disulfide bonds, which are essential for the correct folding and biological activity of many peptides and proteins. Its application is particularly valuable in the synthesis of complex peptides, such as those used in pharmaceuticals, research, and biotechnology.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿8,523.00 |
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Fmoc-Cysteinol(acm)
Fmoc-Cysteinol(acm) is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of cysteinol, where the Fmoc group protects the amino functionality, and the acm (acetamidomethyl) group protects the thiol functionality of the cysteine residue. This protection is crucial to prevent unwanted side reactions during the synthesis process. After the peptide chain is assembled, the Fmoc group can be removed under mild basic conditions, while the acm group can be selectively removed later using specific reagents like iodine or silver salts. This allows for the controlled formation of disulfide bonds, which are essential for the correct folding and biological activity of many peptides and proteins. Its application is particularly valuable in the synthesis of complex peptides, such as those used in pharmaceuticals, research, and biotechnology.
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