N-Boc-cis-4-N-Fmoc-amino-L-proline
97%
- Product Code: 105433
Alias:
N-Boc-cis-4-Fmoc-amino-L-proline
(2S,4S)-N-tert-butoxycarbonyl-4-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine-2-carboxylic acid
CAS:
174148-03-9
| Molecular Weight: | 452.5 g./mol | Molecular Formula: | C₂₅H₂₈N₂O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00673782 | |
| Melting Point: | 150-154 °C(lit.) | Boiling Point: | |
| Density: | 1.33 | Storage Condition: | 2~8°C |
Product Description:
N-Boc-cis-4-N-Fmoc-amino-L-proline is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of L-proline, where the Boc (tert-butoxycarbonyl) and Fmoc (fluorenylmethyloxycarbonyl) groups act as protective groups for the amine functionality. This dual protection allows for selective deprotection during the synthesis process, enabling the stepwise construction of complex peptides. Its application is crucial in the synthesis of proline-rich peptides, which are often found in bioactive molecules and proteins. Additionally, it is employed in the development of peptidomimetics and pharmaceutical compounds, where precise control over amino acid incorporation is essential. The compound’s stability and compatibility with standard peptide synthesis protocols make it a valuable tool in medicinal chemistry and drug discovery research.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿3,960.00 |
+
-
|
N-Boc-cis-4-N-Fmoc-amino-L-proline
N-Boc-cis-4-N-Fmoc-amino-L-proline is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of L-proline, where the Boc (tert-butoxycarbonyl) and Fmoc (fluorenylmethyloxycarbonyl) groups act as protective groups for the amine functionality. This dual protection allows for selective deprotection during the synthesis process, enabling the stepwise construction of complex peptides. Its application is crucial in the synthesis of proline-rich peptides, which are often found in bioactive molecules and proteins. Additionally, it is employed in the development of peptidomimetics and pharmaceutical compounds, where precise control over amino acid incorporation is essential. The compound’s stability and compatibility with standard peptide synthesis protocols make it a valuable tool in medicinal chemistry and drug discovery research.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :