1-Hydroxy-7-azabenzotriazole
99%
- Product Code: 105873
Alias:
1-Hydroxy-7-azobenzotriazole (HOAt); N-Hydroxy-7-azobenzotriazole
CAS:
39968-33-7
| Molecular Weight: | 136.11 g./mol | Molecular Formula: | C₅H₄N₄O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00210053 | |
| Melting Point: | 213-216°C | Boiling Point: | |
| Density: | 0.973 g/mL at 20 °C | Storage Condition: | room temperature |
Product Description:
1-Hydroxy-7-azabenzotriazole is widely used in peptide synthesis as an additive to enhance coupling efficiency. It acts as a catalyst, reducing racemization and improving the yield of peptide bonds during the formation process. This compound is particularly valuable in solid-phase peptide synthesis, where it helps to minimize side reactions and ensures the production of high-purity peptides. Additionally, it is employed in organic synthesis for activating carboxylic acids, making it a versatile reagent in the preparation of amides and esters. Its role in facilitating efficient and selective chemical transformations makes it an essential tool in both academic research and industrial applications.
Product Specification:
| Test | Specification |
|---|---|
| Melting Point | 212-217 |
| Purity (Neutralization Titration) | 98.5-101.5 |
| Purity (LC) | 99 |
| Appearance | White Or Gray Powder |
| Infrared Spectrum | Conforms To Structure |
| Solubility In NaOH Solution | Almost Transparency |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿390.00 |
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| 5.000 | 10-20 days | ฿1,020.00 |
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| 25.000 | 10-20 days | ฿4,180.00 |
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| 100.000 | 10-20 days | ฿16,180.00 |
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1-Hydroxy-7-azabenzotriazole
1-Hydroxy-7-azabenzotriazole is widely used in peptide synthesis as an additive to enhance coupling efficiency. It acts as a catalyst, reducing racemization and improving the yield of peptide bonds during the formation process. This compound is particularly valuable in solid-phase peptide synthesis, where it helps to minimize side reactions and ensures the production of high-purity peptides. Additionally, it is employed in organic synthesis for activating carboxylic acids, making it a versatile reagent in the preparation of amides and esters. Its role in facilitating efficient and selective chemical transformations makes it an essential tool in both academic research and industrial applications.
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