Ac-DEVD-AFC,N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin
>98%
- Product Code: 105887
CAS:
201608-14-2
| Molecular Weight: | 729.61 g./mol | Molecular Formula: | C₃₀H₃₄F₃N₅O₁₃ |
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| Density: | Storage Condition: | -20°C |
Product Description:
This chemical is widely used as a substrate in biochemical assays to measure caspase-3 and caspase-7 activity, which are key enzymes involved in apoptosis. When cleaved by these caspases, it releases a fluorescent product, 7-amido-4-trifluoromethylcoumarin (AFC), allowing for the quantification of enzyme activity. This makes it a valuable tool in apoptosis research, drug screening, and studies of cell death mechanisms. It is also employed in high-throughput screening to identify potential therapeutic compounds that modulate caspase activity. Its sensitivity and specificity make it a preferred choice for in vitro studies of programmed cell death.
Product Specification:
| Test | Specification |
|---|---|
| Purity (%) | 98-100 |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | Ft185,961.10 |
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Ac-DEVD-AFC,N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin
This chemical is widely used as a substrate in biochemical assays to measure caspase-3 and caspase-7 activity, which are key enzymes involved in apoptosis. When cleaved by these caspases, it releases a fluorescent product, 7-amido-4-trifluoromethylcoumarin (AFC), allowing for the quantification of enzyme activity. This makes it a valuable tool in apoptosis research, drug screening, and studies of cell death mechanisms. It is also employed in high-throughput screening to identify potential therapeutic compounds that modulate caspase activity. Its sensitivity and specificity make it a preferred choice for in vitro studies of programmed cell death.
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