(S,R,S)-AHPC-(C3-PEG)2-C6-Cl
≥96%
- Product Code: 105987
CAS:
1835705-61-7
| Molecular Weight: | 749.4400000000001 g./mol | Molecular Formula: | C₃₉H₆₁ClN₄O₆S |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
Used primarily in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the selective degradation of specific proteins by recruiting E3 ubiquitin ligases to the target protein, leading to its ubiquitination and subsequent proteasomal degradation. This mechanism is particularly valuable in cancer research and therapy, where it helps in eliminating disease-causing proteins that are otherwise difficult to target with traditional inhibitors. Additionally, its PEGylated structure enhances solubility and stability, making it more effective in biological systems. This compound is also utilized in chemical biology studies to explore protein function and validate potential drug targets.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿38,600.00 |
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| 0.500 | 10-20 days | ฿163,600.00 |
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(S,R,S)-AHPC-(C3-PEG)2-C6-Cl
Used primarily in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the selective degradation of specific proteins by recruiting E3 ubiquitin ligases to the target protein, leading to its ubiquitination and subsequent proteasomal degradation. This mechanism is particularly valuable in cancer research and therapy, where it helps in eliminating disease-causing proteins that are otherwise difficult to target with traditional inhibitors. Additionally, its PEGylated structure enhances solubility and stability, making it more effective in biological systems. This compound is also utilized in chemical biology studies to explore protein function and validate potential drug targets.
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