(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc
97%
- Product Code: 106008
CAS:
2409007-40-3
| Molecular Weight: | 723.88 g./mol | Molecular Formula: | C₃₇H₄₉N₅O₈S |
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| Density: | Storage Condition: | 2-8°C, dry, sealed |
Product Description:
Used in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the selective degradation of specific proteins by linking a target protein to an E3 ubiquitin ligase, leading to its ubiquitination and subsequent proteasomal degradation. This mechanism is particularly valuable in drug discovery, especially for targeting undruggable proteins in diseases like cancer, neurodegenerative disorders, and autoimmune conditions. Its structure, featuring a Boc-protected amine and PEG linker, ensures stability and efficient cellular uptake, making it a versatile tool in chemical biology and therapeutic research.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | $1,582.12 |
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(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc
Used in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the selective degradation of specific proteins by linking a target protein to an E3 ubiquitin ligase, leading to its ubiquitination and subsequent proteasomal degradation. This mechanism is particularly valuable in drug discovery, especially for targeting undruggable proteins in diseases like cancer, neurodegenerative disorders, and autoimmune conditions. Its structure, featuring a Boc-protected amine and PEG linker, ensures stability and efficient cellular uptake, making it a versatile tool in chemical biology and therapeutic research.
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