Boc-NH-PEG12-CH2CH2COOH
97%
- Product Code: 106118
CAS:
1415981-79-1
| Molecular Weight: | 717.84 g./mol | Molecular Formula: | C₃₂H₆₃NO₁₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD13185149 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, away from light, dry, sealed |
Product Description:
This chemical is widely used in bioconjugation and drug delivery systems due to its polyethylene glycol (PEG) spacer, which enhances solubility and reduces immunogenicity. The Boc (tert-butoxycarbonyl) protecting group allows for selective deprotection, enabling controlled reactions in peptide synthesis. The terminal carboxylic acid group facilitates coupling with amines or other functional groups, making it valuable for creating linkers in antibody-drug conjugates (ADCs) and other targeted therapies. Its PEG chain also improves pharmacokinetics by prolonging circulation time in the body, making it a key component in the development of therapeutic proteins and nanoparticles. Additionally, it is employed in surface modification of biomaterials to enhance biocompatibility and reduce protein adsorption.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿40,500.00 |
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| 0.250 | 10-20 days | ฿62,100.00 |
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Boc-NH-PEG12-CH2CH2COOH
This chemical is widely used in bioconjugation and drug delivery systems due to its polyethylene glycol (PEG) spacer, which enhances solubility and reduces immunogenicity. The Boc (tert-butoxycarbonyl) protecting group allows for selective deprotection, enabling controlled reactions in peptide synthesis. The terminal carboxylic acid group facilitates coupling with amines or other functional groups, making it valuable for creating linkers in antibody-drug conjugates (ADCs) and other targeted therapies. Its PEG chain also improves pharmacokinetics by prolonging circulation time in the body, making it a key component in the development of therapeutic proteins and nanoparticles. Additionally, it is employed in surface modification of biomaterials to enhance biocompatibility and reduce protein adsorption.
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