E3 ligase Ligand 15
97%
- Product Code: 106182
CAS:
2306390-08-7
| Molecular Weight: | 639.53 g./mol | Molecular Formula: | C₃₂H₃₂Cl₂N₄O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32197284 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry, sealed |
Product Description:
Primarily utilized in the field of targeted protein degradation, this compound plays a crucial role in the development of PROTACs (Proteolysis Targeting Chimeras). It functions by recruiting E3 ubiquitin ligases to specific proteins of interest, facilitating their ubiquitination and subsequent degradation by the proteasome. This mechanism is particularly valuable in drug discovery and therapeutic research, especially for targeting proteins that are traditionally considered "undruggable." Its application extends to cancer research, where it helps in degrading oncogenic proteins, and in neurodegenerative disease studies, where it aids in eliminating misfolded or aggregated proteins. Additionally, it is employed in chemical biology to study protein function and interactions, providing insights into cellular pathways and disease mechanisms.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿42,750.00 |
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E3 ligase Ligand 15
Primarily utilized in the field of targeted protein degradation, this compound plays a crucial role in the development of PROTACs (Proteolysis Targeting Chimeras). It functions by recruiting E3 ubiquitin ligases to specific proteins of interest, facilitating their ubiquitination and subsequent degradation by the proteasome. This mechanism is particularly valuable in drug discovery and therapeutic research, especially for targeting proteins that are traditionally considered "undruggable." Its application extends to cancer research, where it helps in degrading oncogenic proteins, and in neurodegenerative disease studies, where it aids in eliminating misfolded or aggregated proteins. Additionally, it is employed in chemical biology to study protein function and interactions, providing insights into cellular pathways and disease mechanisms.
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