Mal-PEG2-Val-Cit-amido-PAB-OH

≥95%

Product Code: 106289

CAS: 2055041-38-6

Molecular Weight:	Molecular Formula:	C₂₉H₄₂N₆O₉
EC Number:	MDL Number:
Melting Point:	Boiling Point:
Density:	Storage Condition:	-20°C, away from light, dry, sealed

Product Description: Used in the development of antibody-drug conjugates (ADCs), this compound serves as a linker to connect cytotoxic drugs to antibodies. It enables targeted delivery of therapeutic agents to specific cells, minimizing damage to healthy tissues. The Val-Cit sequence is cleavable by cathepsin B, an enzyme found in lysosomes, ensuring controlled drug release. The PAB (para-aminobenzyl) group enhances stability in circulation, while the PEG2 spacer improves solubility and reduces aggregation. This makes it a critical component in cancer therapy, enhancing the efficacy and safety of ADCs.

Sizes / Availability / Pricing:

Size (g)	Availability	Price	Quantity
0.050	10-20 days	฿30,600.00	+ -

Mal-PEG2-Val-Cit-amido-PAB-OH

Used in the development of antibody-drug conjugates (ADCs), this compound serves as a linker to connect cytotoxic drugs to antibodies. It enables targeted delivery of therapeutic agents to specific cells, minimizing damage to healthy tissues. The Val-Cit sequence is cleavable by cathepsin B, an enzyme found in lysosomes, ensuring controlled drug release. The PAB (para-aminobenzyl) group enhances stability in circulation, while the PEG2 spacer improves solubility and reduces aggregation. This makes it a critical component in cancer therapy, enhancing the efficacy and safety of ADCs.

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