VH-298
≥99%
- Product Code: 106537
CAS:
2097381-85-4
| Molecular Weight: | 523.65 g./mol | Molecular Formula: | C₂₇H₃₃N₅O₄S |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
VH-298 is primarily used in biochemical research to study the hypoxia-inducible factor (HIF) pathway, which plays a critical role in cellular responses to low oxygen levels. It functions as a potent and selective inhibitor of the von Hippel-Lindau (VHL) E3 ubiquitin ligase, a key regulator of HIF stability. By inhibiting VHL, VH-298 stabilizes HIF proteins, allowing researchers to investigate their role in processes such as angiogenesis, metabolism, and tumor growth. This makes it a valuable tool for understanding diseases like cancer, where HIF signaling is often dysregulated. Additionally, VH-298 is used in drug discovery efforts aimed at developing therapies targeting the HIF pathway. Its ability to modulate hypoxia-related pathways also extends its application to studies in ischemic conditions and other oxygen-sensitive biological processes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.002 | 10-20 days | ฿5,958.00 |
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| 0.005 | 10-20 days | ฿8,955.00 |
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VH-298
VH-298 is primarily used in biochemical research to study the hypoxia-inducible factor (HIF) pathway, which plays a critical role in cellular responses to low oxygen levels. It functions as a potent and selective inhibitor of the von Hippel-Lindau (VHL) E3 ubiquitin ligase, a key regulator of HIF stability. By inhibiting VHL, VH-298 stabilizes HIF proteins, allowing researchers to investigate their role in processes such as angiogenesis, metabolism, and tumor growth. This makes it a valuable tool for understanding diseases like cancer, where HIF signaling is often dysregulated. Additionally, VH-298 is used in drug discovery efforts aimed at developing therapies targeting the HIF pathway. Its ability to modulate hypoxia-related pathways also extends its application to studies in ischemic conditions and other oxygen-sensitive biological processes.
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