(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2)
98%
- Product Code: 106729
CAS:
2245697-83-8
| Molecular Weight: | 566.16 g./mol | Molecular Formula: | C₂₇H₄₀ClN₅O₄S |
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| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key ligand that binds to the von Hippel-Lindau (VHL) E3 ubiquitin ligase, enabling the recruitment of specific proteins of interest for ubiquitination and subsequent degradation by the proteasome. Its application is significant in drug discovery, especially for targeting undruggable proteins or those involved in disease pathways, such as cancer, neurodegenerative disorders, and inflammatory conditions. The compound's ability to facilitate selective protein degradation makes it a valuable tool in both academic research and therapeutic development.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿54,990.00 |
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(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2)
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key ligand that binds to the von Hippel-Lindau (VHL) E3 ubiquitin ligase, enabling the recruitment of specific proteins of interest for ubiquitination and subsequent degradation by the proteasome. Its application is significant in drug discovery, especially for targeting undruggable proteins or those involved in disease pathways, such as cancer, neurodegenerative disorders, and inflammatory conditions. The compound's ability to facilitate selective protein degradation makes it a valuable tool in both academic research and therapeutic development.
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