Azido-PEG3-Sulfone-PEG4-acid
≥95%
- Product Code: 107692
CAS:
2055024-42-3
| Molecular Weight: | 515.58 g./mol | Molecular Formula: | C₁₉H₃₇N₃O₁₁S |
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| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
This compound is widely used in bioconjugation and chemical biology due to its reactive azido group and sulfone functionality. It serves as a linker or crosslinker in the development of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted cancer therapy. The PEG chains enhance solubility and reduce immunogenicity, making it suitable for in vivo applications. Additionally, it is utilized in click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), for labeling biomolecules such as proteins, peptides, and nucleic acids. Its sulfone group can also participate in nucleophilic substitution reactions, allowing for further functionalization. This makes it a versatile tool in drug delivery systems, diagnostics, and proteomics research.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿14,400.00 |
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Azido-PEG3-Sulfone-PEG4-acid
This compound is widely used in bioconjugation and chemical biology due to its reactive azido group and sulfone functionality. It serves as a linker or crosslinker in the development of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted cancer therapy. The PEG chains enhance solubility and reduce immunogenicity, making it suitable for in vivo applications. Additionally, it is utilized in click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), for labeling biomolecules such as proteins, peptides, and nucleic acids. Its sulfone group can also participate in nucleophilic substitution reactions, allowing for further functionalization. This makes it a versatile tool in drug delivery systems, diagnostics, and proteomics research.
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