BI-2545

≥99%

  • Product Code: 107789
  CAS:    2162961-71-7
Molecular Weight: 527.42 g./mol Molecular Formula: C₂₃H₁₉F₆N₅O₃
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, sealed, dry
Product Description: BI-2545 is primarily utilized in biochemical research as a selective inhibitor of PLK1 (Polo-like kinase 1). This enzyme plays a critical role in cell division, making BI-2545 a valuable tool for studying cell cycle regulation and mitosis. Researchers use it to investigate the effects of PLK1 inhibition on cancer cells, as PLK1 is often overexpressed in various tumors. By blocking PLK1 activity, BI-2545 helps in understanding its role in tumor growth and progression, potentially aiding in the development of targeted cancer therapies. Additionally, it is employed in preclinical studies to evaluate its efficacy and mechanisms of action in inhibiting cancer cell proliferation.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days ฿8,550.00
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0.025 10-20 days ฿33,750.00
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0.100 10-20 days ฿103,500.00
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BI-2545
BI-2545 is primarily utilized in biochemical research as a selective inhibitor of PLK1 (Polo-like kinase 1). This enzyme plays a critical role in cell division, making BI-2545 a valuable tool for studying cell cycle regulation and mitosis. Researchers use it to investigate the effects of PLK1 inhibition on cancer cells, as PLK1 is often overexpressed in various tumors. By blocking PLK1 activity, BI-2545 helps in understanding its role in tumor growth and progression, potentially aiding in the development of targeted cancer therapies. Additionally, it is employed in preclinical studies to evaluate its efficacy and mechanisms of action in inhibiting cancer cell proliferation.
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