H-89

98%

  • Product Code: 108478
  Alias:    Related CAS numbers: 1000995-75-4(free state); 130964-39-5(hydrochloride); h89; N-(2-(4-Bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide; N-[2-[ P-Bromophenylpropenylamino]ethyl]-5-isoquinolinesulfonamide
  CAS:    127243-85-0
  Properties:    H2O: ≥10 mg/mL
Molecular Weight: 446.36 g./mol Molecular Formula: C₂₀H₂₀BrN₃O₂S
EC Number: MDL Number: MFCD00214119
Melting Point: 195-200 °C Boiling Point: 639.7 ºC
Density: 1.436 g/cm3 Storage Condition: 2-8°C, dry, sealed
Product Description: H-89 is widely utilized in biochemical research due to its role as a potent and selective inhibitor of protein kinase A (PKA). It is particularly valuable in studies aimed at understanding the signaling pathways and cellular processes regulated by PKA. Researchers employ H-89 to investigate the effects of PKA inhibition on various physiological functions, including cell proliferation, differentiation, and metabolism. Additionally, it is used in neuroscience to explore the involvement of PKA in neuronal signaling and synaptic plasticity. H-89 also finds application in pharmacological studies, where it helps in identifying potential therapeutic targets by elucidating the role of PKA in disease mechanisms. Its ability to selectively inhibit PKA makes it a crucial tool in dissecting complex signaling networks and understanding the molecular basis of PKA-mediated cellular responses.
Product Specification:
Test Specification
Appearance Yellow Solid
Purity (%) 97.5-100
Infrared Spectrum Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.010 10-20 days ฿2,240.00
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0.050 10-20 days ฿8,420.00
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0.250 10-20 days ฿29,500.00
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H-89
H-89 is widely utilized in biochemical research due to its role as a potent and selective inhibitor of protein kinase A (PKA). It is particularly valuable in studies aimed at understanding the signaling pathways and cellular processes regulated by PKA. Researchers employ H-89 to investigate the effects of PKA inhibition on various physiological functions, including cell proliferation, differentiation, and metabolism. Additionally, it is used in neuroscience to explore the involvement of PKA in neuronal signaling and synaptic plasticity. H-89 also finds application in pharmacological studies, where it helps in identifying potential therapeutic targets by elucidating the role of PKA in disease mechanisms. Its ability to selectively inhibit PKA makes it a crucial tool in dissecting complex signaling networks and understanding the molecular basis of PKA-mediated cellular responses.
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