H2N-PEG24-CH2CH2COOtBu
95%
- Product Code: 108487
CAS:
2170987-96-7
| Molecular Weight: | 1202.46 g./mol | Molecular Formula: | C₅₅H₁₁₁NO₂₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD11041158 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
This chemical is widely used in bioconjugation and drug delivery systems due to its polyethylene glycol (PEG) chain, which enhances solubility and stability of biomolecules. The amine group (H2N-) allows for easy attachment to proteins, peptides, or other targeting molecules, while the t-butyl ester (COOtBu) provides a protective group that can be removed under specific conditions to expose a reactive carboxyl group. This makes it valuable in creating prodrugs or controlled-release formulations. Additionally, its long PEG spacer improves biocompatibility and reduces immunogenicity, making it suitable for therapeutic applications such as antibody-drug conjugates, nanoparticles, and targeted cancer therapies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿14,400.00 |
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H2N-PEG24-CH2CH2COOtBu
This chemical is widely used in bioconjugation and drug delivery systems due to its polyethylene glycol (PEG) chain, which enhances solubility and stability of biomolecules. The amine group (H2N-) allows for easy attachment to proteins, peptides, or other targeting molecules, while the t-butyl ester (COOtBu) provides a protective group that can be removed under specific conditions to expose a reactive carboxyl group. This makes it valuable in creating prodrugs or controlled-release formulations. Additionally, its long PEG spacer improves biocompatibility and reduces immunogenicity, making it suitable for therapeutic applications such as antibody-drug conjugates, nanoparticles, and targeted cancer therapies.
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