IACS-8968 (S-enantiomer) (IDO/TDO Inhibitor (S-enantiomer))
98%
- Product Code: 108563
CAS:
2239305-70-3
| Molecular Weight: | 381.35 g./mol | Molecular Formula: | C₁₇H₁₈F₃N₅O₂ |
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| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
IACS-8968 (S-enantiomer) is primarily used in research and therapeutic development as an inhibitor of IDO (indoleamine 2,3-dioxygenase) and TDO (tryptophan 2,3-dioxygenase) enzymes. These enzymes play a critical role in immune suppression by metabolizing tryptophan into kynurenine, which inhibits T-cell activation and promotes tumor immune evasion. By blocking IDO and TDO, this compound enhances immune responses, making it a promising candidate for cancer immunotherapy. It is particularly studied in combination with other immunotherapies to improve their efficacy in treating various cancers. Additionally, its S-enantiomer form is specifically targeted for its optimized potency and selectivity in preclinical studies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿130,920.00 |
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IACS-8968 (S-enantiomer) (IDO/TDO Inhibitor (S-enantiomer))
IACS-8968 (S-enantiomer) is primarily used in research and therapeutic development as an inhibitor of IDO (indoleamine 2,3-dioxygenase) and TDO (tryptophan 2,3-dioxygenase) enzymes. These enzymes play a critical role in immune suppression by metabolizing tryptophan into kynurenine, which inhibits T-cell activation and promotes tumor immune evasion. By blocking IDO and TDO, this compound enhances immune responses, making it a promising candidate for cancer immunotherapy. It is particularly studied in combination with other immunotherapies to improve their efficacy in treating various cancers. Additionally, its S-enantiomer form is specifically targeted for its optimized potency and selectivity in preclinical studies.
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