ICRF-193
98%
- Product Code: 108572
CAS:
21416-88-6
Molecular Weight: | 282.30 g./mol | Molecular Formula: | C₁₂H₁₈N₄O₄ |
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Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
ICRF-193 is primarily used in biochemical and cancer research due to its ability to inhibit topoisomerase II, an enzyme crucial for DNA replication and cell division. This property makes it a valuable tool for studying cell cycle regulation and the mechanisms of DNA damage. Researchers utilize ICRF-193 to induce cell cycle arrest, particularly in the G2/M phase, to investigate how cells respond to DNA stress and to explore potential therapeutic strategies for cancer. Its role in stabilizing the topoisomerase II-DNA complex without causing DNA breaks distinguishes it from other topoisomerase inhibitors, providing unique insights into cellular processes and drug development.
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.001 | 10-20 days | ฿53,136.00 |
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ICRF-193
ICRF-193 is primarily used in biochemical and cancer research due to its ability to inhibit topoisomerase II, an enzyme crucial for DNA replication and cell division. This property makes it a valuable tool for studying cell cycle regulation and the mechanisms of DNA damage. Researchers utilize ICRF-193 to induce cell cycle arrest, particularly in the G2/M phase, to investigate how cells respond to DNA stress and to explore potential therapeutic strategies for cancer. Its role in stabilizing the topoisomerase II-DNA complex without causing DNA breaks distinguishes it from other topoisomerase inhibitors, providing unique insights into cellular processes and drug development.
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