MC-Sq-Cit-PAB-Gefitinib
≥98%
- Product Code: 108891
CAS:
1941168-63-3
| Molecular Weight: | 1000.53 g./mol | Molecular Formula: | C₅₀H₆₁ClFN₁₀O₉ |
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| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
MC-Sq-Cit-PAB-Gefitinib is primarily utilized in the field of targeted cancer therapy, specifically in the development of antibody-drug conjugates (ADCs). This compound acts as a linker-payload, where the Gefitinib component serves as a potent tyrosine kinase inhibitor targeting the epidermal growth factor receptor (EGFR). The MC-Sq-Cit-PAB segment functions as a cleavable linker, enabling the controlled release of Gefitinib at the tumor site. This targeted approach enhances the efficacy of the drug while minimizing off-target effects, making it a valuable tool in treating EGFR-positive cancers such as non-small cell lung cancer (NSCLC). Its application in ADCs represents a significant advancement in precision medicine, offering improved therapeutic outcomes for patients.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿67,500.00 |
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MC-Sq-Cit-PAB-Gefitinib
MC-Sq-Cit-PAB-Gefitinib is primarily utilized in the field of targeted cancer therapy, specifically in the development of antibody-drug conjugates (ADCs). This compound acts as a linker-payload, where the Gefitinib component serves as a potent tyrosine kinase inhibitor targeting the epidermal growth factor receptor (EGFR). The MC-Sq-Cit-PAB segment functions as a cleavable linker, enabling the controlled release of Gefitinib at the tumor site. This targeted approach enhances the efficacy of the drug while minimizing off-target effects, making it a valuable tool in treating EGFR-positive cancers such as non-small cell lung cancer (NSCLC). Its application in ADCs represents a significant advancement in precision medicine, offering improved therapeutic outcomes for patients.
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