N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
95%
- Product Code: 109002
CAS:
2245697-85-0
| Molecular Weight: | 587.02 g./mol | Molecular Formula: | C₂₅H₃₅ClN₄O₁₀ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31656718 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, store under inert gas |
Product Description:
This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿28,611.00 |
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| 0.250 | 10-20 days | ฿42,912.00 |
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N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.
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