NSC617145(WRN inhibitor)

98%

  • Product Code: 109150
  CAS:    203115-63-3
Molecular Weight: 400.04 g./mol Molecular Formula: C₁₃H₁₀Cl₄N₂O₄
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20°C, airtight, dry
Product Description: NSC617145, as a WRN inhibitor, is primarily used in research focused on targeting cancers with microsatellite instability (MSI). It works by inhibiting the WRN helicase, which is essential for the survival of MSI-high cancer cells. This makes it a potential therapeutic agent for treating colorectal, gastric, and endometrial cancers that exhibit MSI. Additionally, it is studied for its role in synthetic lethality, where it selectively kills cancer cells while sparing normal cells, offering a promising approach for precision medicine in oncology. Its application extends to understanding DNA repair mechanisms and developing strategies to combat treatment-resistant cancers.
Product Specification:
Test Specification
Appearance White To Light Brown Powder
Purity (%) 97.5-100
Infrared Spectrum Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.010 10-20 days $309.39
+
-
0.050 10-20 days $1,353.59
+
-
NSC617145(WRN inhibitor)
NSC617145, as a WRN inhibitor, is primarily used in research focused on targeting cancers with microsatellite instability (MSI). It works by inhibiting the WRN helicase, which is essential for the survival of MSI-high cancer cells. This makes it a potential therapeutic agent for treating colorectal, gastric, and endometrial cancers that exhibit MSI. Additionally, it is studied for its role in synthetic lethality, where it selectively kills cancer cells while sparing normal cells, offering a promising approach for precision medicine in oncology. Its application extends to understanding DNA repair mechanisms and developing strategies to combat treatment-resistant cancers.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Cart

No products

Subtotal: $0.00
$0.00 Total :

The availability date depends on real-time stock, and any changes after payment will be notified within 30 minutes
You can choose the delivery date on the next page