SAR-020106
99%
- Product Code: 109280
CAS:
1184843-57-9
| Molecular Weight: | 382.85 g./mol | Molecular Formula: | C₁₉H₁₉ClN₆O |
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| Density: | Storage Condition: | -20℃ |
Product Description:
SAR-020106 is primarily investigated for its potential therapeutic applications in the field of cancer research. It functions as an ATM kinase inhibitor, which makes it a promising candidate for sensitizing cancer cells to radiation and chemotherapy. By inhibiting ATM kinase, it disrupts the DNA damage response pathway, preventing cancer cells from repairing DNA damage effectively. This mechanism enhances the efficacy of treatments like radiotherapy and certain chemotherapeutic agents, particularly in tumors that rely on intact DNA repair mechanisms for survival. Research is ongoing to explore its use in combination therapies for cancers such as glioblastoma, breast cancer, and other solid tumors. Additionally, it is being studied for its role in overcoming resistance to conventional treatments, offering a potential strategy to improve outcomes in challenging cases. Its application is still largely confined to preclinical studies, but it holds significant promise for future clinical development.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿19,330.00 |
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SAR-020106
SAR-020106 is primarily investigated for its potential therapeutic applications in the field of cancer research. It functions as an ATM kinase inhibitor, which makes it a promising candidate for sensitizing cancer cells to radiation and chemotherapy. By inhibiting ATM kinase, it disrupts the DNA damage response pathway, preventing cancer cells from repairing DNA damage effectively. This mechanism enhances the efficacy of treatments like radiotherapy and certain chemotherapeutic agents, particularly in tumors that rely on intact DNA repair mechanisms for survival. Research is ongoing to explore its use in combination therapies for cancers such as glioblastoma, breast cancer, and other solid tumors. Additionally, it is being studied for its role in overcoming resistance to conventional treatments, offering a potential strategy to improve outcomes in challenging cases. Its application is still largely confined to preclinical studies, but it holds significant promise for future clinical development.
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