Selumetinib sulfate (AZD6244 sulfate)
98%
- Product Code: 109590
CAS:
943332-08-9
| Molecular Weight: | 555.76 g./mol | Molecular Formula: | C₁₇H₁₇BrClFN₄O₇S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
Selumetinib sulfate is primarily used in the treatment of certain types of cancer, particularly in patients with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas. It works by inhibiting the MEK enzyme, which is part of the MAPK/ERK pathway, a signaling pathway that can promote cancer cell growth and survival. By blocking this pathway, selumetinib sulfate helps to reduce tumor size and alleviate symptoms associated with these tumors. It is often prescribed for pediatric patients when surgical removal of the tumors is not feasible. Additionally, ongoing research is exploring its potential efficacy in other cancers, such as melanoma, non-small cell lung cancer, and thyroid cancer, where the MAPK/ERK pathway is dysregulated.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿9,423.00 |
+
-
|
Selumetinib sulfate (AZD6244 sulfate)
Selumetinib sulfate is primarily used in the treatment of certain types of cancer, particularly in patients with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas. It works by inhibiting the MEK enzyme, which is part of the MAPK/ERK pathway, a signaling pathway that can promote cancer cell growth and survival. By blocking this pathway, selumetinib sulfate helps to reduce tumor size and alleviate symptoms associated with these tumors. It is often prescribed for pediatric patients when surgical removal of the tumors is not feasible. Additionally, ongoing research is exploring its potential efficacy in other cancers, such as melanoma, non-small cell lung cancer, and thyroid cancer, where the MAPK/ERK pathway is dysregulated.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :