Thiazolyl blue tetrazolium bromide (MTT)
98%
- Product Code: 110475
Alias:
Thiazolium blue (MTT); 3-(4,5-Dimethyl-2-thiazole)-2,5-diphenyl bromide tetrazolium bromide, thiazolium blue, bromide thiazole blue tetrazolium
CAS:
298-93-1
| Molecular Weight: | 414.32 g./mol | Molecular Formula: | C₁₈H₁₆BrN₅S |
|---|---|---|---|
| EC Number: | 206-069-5 | MDL Number: | MFCD00011964 |
| Melting Point: | 195 °C (dec.)(lit.) | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
MTT is widely used in cell biology and biomedical research as a key reagent for assessing cell viability and proliferation. It is particularly valuable in the MTT assay, where it serves as a substrate to measure mitochondrial activity in living cells. When added to cell cultures, MTT is reduced by metabolically active cells into a purple formazan product, which can be quantified spectrophotometrically. This assay is commonly employed in drug screening, cytotoxicity studies, and cancer research to evaluate the effects of various compounds on cell growth and survival. Its simplicity, reliability, and sensitivity make it a staple in laboratories studying cellular responses to treatments or environmental conditions.
Product Specification:
| Test | Specification |
|---|---|
| Purity (Titration With Agno3) | 97.5-102.5 |
| Melting Point | 195 Degree Celsius |
| Solubility In Hot Water | Clear |
| Appearance | Yellow To Dark Yellow Powder |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | $18.88 |
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| 1.000 | 10-20 days | $31.07 |
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| 5.000 | 10-20 days | $110.51 |
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| 25.000 | 10-20 days | $478.20 |
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| 100.000 | 10-20 days | $1,603.71 |
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Thiazolyl blue tetrazolium bromide (MTT)
MTT is widely used in cell biology and biomedical research as a key reagent for assessing cell viability and proliferation. It is particularly valuable in the MTT assay, where it serves as a substrate to measure mitochondrial activity in living cells. When added to cell cultures, MTT is reduced by metabolically active cells into a purple formazan product, which can be quantified spectrophotometrically. This assay is commonly employed in drug screening, cytotoxicity studies, and cancer research to evaluate the effects of various compounds on cell growth and survival. Its simplicity, reliability, and sensitivity make it a staple in laboratories studying cellular responses to treatments or environmental conditions.
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