(-)-JQ1

98%

  • Product Code: 110567
  CAS:    1268524-71-5
Molecular Weight: 456.99 g./mol Molecular Formula: C₂₃H₂₅ClN₄O₂S
EC Number: MDL Number: MFCD22124456
Melting Point: Boiling Point:
Density: Storage Condition:  -20°C
Product Description: Used primarily in cancer research, it acts as a potent inhibitor of BET proteins, which play a crucial role in regulating gene expression. By blocking these proteins, it disrupts the growth and survival of cancer cells, particularly in hematologic malignancies and certain solid tumors. Additionally, it has shown promise in studies targeting inflammatory diseases and HIV latency, offering potential therapeutic avenues. Its ability to modulate gene expression also makes it a valuable tool in epigenetic research, aiding in the understanding of chromatin biology and transcriptional regulation.
Product Specification:
Test Specification
Appearance White To Yellow To Beige Solid Or Powder
Purity (%) 97.5-100
Nmr Consistent With Structure
Infrared Spectrum Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days Ft59,904.04
+
-
0.025 10-20 days Ft271,292.04
+
-
(-)-JQ1
Used primarily in cancer research, it acts as a potent inhibitor of BET proteins, which play a crucial role in regulating gene expression. By blocking these proteins, it disrupts the growth and survival of cancer cells, particularly in hematologic malignancies and certain solid tumors. Additionally, it has shown promise in studies targeting inflammatory diseases and HIV latency, offering potential therapeutic avenues. Its ability to modulate gene expression also makes it a valuable tool in epigenetic research, aiding in the understanding of chromatin biology and transcriptional regulation.
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