4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
98%
- Product Code: 111546
Alias:
4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfonic acid-N-hydroxysuccinimide ester sodium salt
CAS:
92921-24-9
| Molecular Weight: | 436.37 g./mol | Molecular Formula: | C₁₆H₁₇N₂NaO₉S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00054978 | |
| Melting Point: | >270°C (dec.) | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
This chemical is widely used in bioconjugation and protein labeling applications. Its maleimide group reacts specifically with thiol groups (-SH) in cysteine residues of proteins, enabling the formation of stable thioether bonds. The NHS ester moiety allows for efficient conjugation with primary amines (-NH2) present in lysine residues or at the N-terminus of proteins. The sulfonate group enhances water solubility, making it suitable for aqueous reaction conditions. It is commonly employed in the preparation of antibody-drug conjugates (ADCs), enzyme labeling, and immobilization of biomolecules on solid supports for diagnostic assays. Its dual reactivity makes it a versatile tool in the development of bioconjugates for therapeutic and research purposes.
Product Specification:
| Test | Specification |
|---|---|
| Purity (%) | 97.5-100 |
| Appearance | White To Brown Powder |
| Proton Nmr Spectrum | Conforms To Structure |
| Solubility In H2O | Colorless Clear To Light Yellow, 2.5 Mg/Ml, H2O |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | ฿2,990.00 |
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| 0.100 | 10-20 days | ฿6,040.00 |
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| 0.500 | 10-20 days | ฿14,990.00 |
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4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
This chemical is widely used in bioconjugation and protein labeling applications. Its maleimide group reacts specifically with thiol groups (-SH) in cysteine residues of proteins, enabling the formation of stable thioether bonds. The NHS ester moiety allows for efficient conjugation with primary amines (-NH2) present in lysine residues or at the N-terminus of proteins. The sulfonate group enhances water solubility, making it suitable for aqueous reaction conditions. It is commonly employed in the preparation of antibody-drug conjugates (ADCs), enzyme labeling, and immobilization of biomolecules on solid supports for diagnostic assays. Its dual reactivity makes it a versatile tool in the development of bioconjugates for therapeutic and research purposes.
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