(S)-(−)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline
95.0% (qNMR)
- Product Code: 114571
CAS:
149341-33-3
| Molecular Weight: | 439.49 g./mol | Molecular Formula: | C₃₁H₂₂NP |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD01073773 | |
| Melting Point: | 220-230 °C | Boiling Point: | 588.1±38.0 °C(Predicted) |
| Density: | Storage Condition: | room temperature |
Product Description:
This chemical is primarily utilized as a chiral ligand in asymmetric synthesis, particularly in transition metal-catalyzed reactions. Its structure, featuring a diphenylphosphino group and an isoquinoline moiety, makes it highly effective in inducing enantioselectivity in various catalytic processes. It is commonly employed in asymmetric hydrogenation reactions, where it helps produce chiral molecules with high enantiomeric purity, which are crucial in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). Additionally, it finds applications in asymmetric carbon-carbon bond-forming reactions, such as cross-coupling and allylic substitution, contributing to the efficient synthesis of complex organic molecules with specific stereochemistry. Its robust performance in these reactions makes it a valuable tool in the development of enantioselective catalysts for fine chemical and drug manufacturing.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Light Yellow Powder Or Crystals |
| Purity (%) | 94.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | £144.52 |
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| 0.050 | 10-20 days | £422.94 |
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(S)-(−)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline
This chemical is primarily utilized as a chiral ligand in asymmetric synthesis, particularly in transition metal-catalyzed reactions. Its structure, featuring a diphenylphosphino group and an isoquinoline moiety, makes it highly effective in inducing enantioselectivity in various catalytic processes. It is commonly employed in asymmetric hydrogenation reactions, where it helps produce chiral molecules with high enantiomeric purity, which are crucial in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). Additionally, it finds applications in asymmetric carbon-carbon bond-forming reactions, such as cross-coupling and allylic substitution, contributing to the efficient synthesis of complex organic molecules with specific stereochemistry. Its robust performance in these reactions makes it a valuable tool in the development of enantioselective catalysts for fine chemical and drug manufacturing.
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