2-(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid

97%

  • Product Code: 115293
  CAS:    56059-30-4
Molecular Weight: 188.11 g./mol Molecular Formula: C₆H₅FN₂O₄
EC Number: MDL Number: MFCD00832183
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, dry and sealed
Product Description: This compound is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of antiviral and anticancer agents. Its structure, featuring a fluorinated pyrimidine core, is particularly valuable in the development of nucleoside analogs, which are crucial for inhibiting viral replication and targeting cancer cells. Researchers leverage its properties to design prodrugs that can be metabolically activated within the body, enhancing therapeutic efficacy. Additionally, it is employed in biochemical studies to investigate enzyme mechanisms and interactions, particularly those involving thymidylate synthase, an enzyme critical for DNA synthesis. Its applications also extend to the development of diagnostic tools and imaging agents for detecting disease markers.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.250 10-20 days £123.96
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1.000 10-20 days £311.64
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5.000 10-20 days £1,039.75
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2-(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid
This compound is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of antiviral and anticancer agents. Its structure, featuring a fluorinated pyrimidine core, is particularly valuable in the development of nucleoside analogs, which are crucial for inhibiting viral replication and targeting cancer cells. Researchers leverage its properties to design prodrugs that can be metabolically activated within the body, enhancing therapeutic efficacy. Additionally, it is employed in biochemical studies to investigate enzyme mechanisms and interactions, particularly those involving thymidylate synthase, an enzyme critical for DNA synthesis. Its applications also extend to the development of diagnostic tools and imaging agents for detecting disease markers.
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