4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
≥98%
- Product Code: 118657
CAS:
64987-82-2
| Molecular Weight: | 237.26 g./mol | Molecular Formula: | C₁₂H₁₅NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD03093740 | |
| Melting Point: | 91°C(lit.) | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in bioconjugation and protein labeling, this compound serves as a linker in the development of antibody-drug conjugates (ADCs) and other therapeutic molecules. Its maleimide group reacts selectively with thiol groups in cysteine residues, enabling stable covalent attachment to proteins or peptides. This property is valuable in drug delivery systems, where precise targeting and controlled release are essential. Additionally, it finds applications in the preparation of affinity chromatography resins, aiding in the purification of biomolecules. Its cyclohexane structure provides rigidity, enhancing stability in various biochemical environments.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Almost White Powder To Crystal |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | $11.40 |
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| 0.200 | 10-20 days | $38.40 |
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4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
Used primarily in bioconjugation and protein labeling, this compound serves as a linker in the development of antibody-drug conjugates (ADCs) and other therapeutic molecules. Its maleimide group reacts selectively with thiol groups in cysteine residues, enabling stable covalent attachment to proteins or peptides. This property is valuable in drug delivery systems, where precise targeting and controlled release are essential. Additionally, it finds applications in the preparation of affinity chromatography resins, aiding in the purification of biomolecules. Its cyclohexane structure provides rigidity, enhancing stability in various biochemical environments.
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