p-Toluenesulfonyl isocyanate

96%

  • Product Code: 119504
  Alias:    4-toluenesulfonyl isocyanate; p-toluenesulfonyl isocyanate
  CAS:    4083-64-1
Molecular Weight: 197.21 g./mol Molecular Formula: C₈H₇NO₃S
EC Number: 223-810-8 MDL Number: MFCD00002030
Melting Point: 5°C Boiling Point: 275-278 °C(lit.)
Density: 1.291 g/mL at 25 °C(lit.) Storage Condition: room temperature, dry
Product Description: Used primarily as a reagent in organic synthesis, this chemical is highly effective for introducing the tosyl group into various compounds. It is commonly employed in the protection of amines, where it reacts to form stable tosylamides, which can be later deprotected to regenerate the original amine. Additionally, it finds application in the synthesis of sulfonamides, which are valuable in pharmaceutical chemistry due to their biological activity. Its reactivity with alcohols and phenols also makes it useful for preparing sulfonate esters, which serve as intermediates in the production of dyes, polymers, and other specialty chemicals. In peptide chemistry, it is utilized for modifying amino acids to enhance stability or alter reactivity. Its versatility and efficiency make it a key tool in both academic research and industrial processes.
Product Specification:
Test Specification
Purity (GC) 96-100
Refractive Index N20/D 1.534-1.536
Appearance Colorless Liquid
Infrared Spectrum Conforms To Structure
Note This Product Is Low Melting Point Solid, May Change State In Different Environments (Solid, Liquid Or Semi-Solid)
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
25.000 10-20 days ฿320.00
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100.000 10-20 days ฿780.00
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500.000 10-20 days ฿2,870.00
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-
2500.000 10-20 days ฿10,440.00
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p-Toluenesulfonyl isocyanate
Used primarily as a reagent in organic synthesis, this chemical is highly effective for introducing the tosyl group into various compounds. It is commonly employed in the protection of amines, where it reacts to form stable tosylamides, which can be later deprotected to regenerate the original amine. Additionally, it finds application in the synthesis of sulfonamides, which are valuable in pharmaceutical chemistry due to their biological activity. Its reactivity with alcohols and phenols also makes it useful for preparing sulfonate esters, which serve as intermediates in the production of dyes, polymers, and other specialty chemicals. In peptide chemistry, it is utilized for modifying amino acids to enhance stability or alter reactivity. Its versatility and efficiency make it a key tool in both academic research and industrial processes.
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