4-Nitrobenzenesulfonyl chloride

99%

  • Product Code: 119547
  CAS:    98-74-8
Molecular Weight: 221.62 g./mol Molecular Formula: C₆H₄ClNO₄S
EC Number: 202-697-9 MDL Number: MFCD00007445
Melting Point: 75 °C Boiling Point: 143-144 °C (1.5002 mmHg)
Density: Storage Condition: Room temperature, dry, sealed
Product Description: Used primarily as a reagent in organic synthesis, this compound is valuable for introducing the 4-nitrobenzenesulfonyl (nosyl) protecting group to amines. It is particularly effective in peptide chemistry, where it helps protect amino groups during synthesis, allowing selective reactions to occur without interference. Additionally, it is employed in the preparation of sulfonamides, which are important in pharmaceutical applications due to their antibacterial properties. Its reactivity with nucleophiles makes it useful in cross-coupling reactions and in the modification of biomolecules.
Product Specification:
Test Specification
Melting Point 77-80
Purity (GC) 98-100
Purity (Titration With AgNO3) 97.5-102.5
Appearance Yellow To Brown Powder Or Crystals
Infrared Spectrum Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
5.000 10-20 days ฿380.00
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25.000 10-20 days ฿780.00
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100.000 10-20 days ฿1,680.00
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500.000 10-20 days ฿6,800.00
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4-Nitrobenzenesulfonyl chloride
Used primarily as a reagent in organic synthesis, this compound is valuable for introducing the 4-nitrobenzenesulfonyl (nosyl) protecting group to amines. It is particularly effective in peptide chemistry, where it helps protect amino groups during synthesis, allowing selective reactions to occur without interference. Additionally, it is employed in the preparation of sulfonamides, which are important in pharmaceutical applications due to their antibacterial properties. Its reactivity with nucleophiles makes it useful in cross-coupling reactions and in the modification of biomolecules.
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