7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
≥95%
- Product Code: 120805
CAS:
768350-54-5
| Molecular Weight: | 454.29 g./mol | Molecular Formula: | C₂₂H₁₇BrFN₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD19440903 | |
| Melting Point: | Boiling Point: | 541.094°C at 760 mmHg | |
| Density: | Storage Condition: | Room temperature, away from light, stored in an inert gas |
Product Description:
This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of targeted therapeutic agents, particularly in the development of kinase inhibitors. Kinase inhibitors are crucial in treating various types of cancers, as they block specific enzymes involved in the growth and proliferation of cancer cells. The structural features of this compound, including the quinazoline core and substituted aromatic rings, make it a valuable scaffold for designing molecules that can selectively inhibit tyrosine kinases or other related enzymes. Researchers often modify and optimize this compound to enhance its binding affinity, selectivity, and pharmacokinetic properties, aiming to create effective and safe drugs for oncology applications. Additionally, its bromo and fluoro substituents provide reactive sites for further chemical modifications, enabling the exploration of diverse derivatives with potential biological activity.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿5,904.00 |
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| 0.250 | 10-20 days | ฿9,846.00 |
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| 1.000 | 10-20 days | ฿32,805.00 |
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7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of targeted therapeutic agents, particularly in the development of kinase inhibitors. Kinase inhibitors are crucial in treating various types of cancers, as they block specific enzymes involved in the growth and proliferation of cancer cells. The structural features of this compound, including the quinazoline core and substituted aromatic rings, make it a valuable scaffold for designing molecules that can selectively inhibit tyrosine kinases or other related enzymes. Researchers often modify and optimize this compound to enhance its binding affinity, selectivity, and pharmacokinetic properties, aiming to create effective and safe drugs for oncology applications. Additionally, its bromo and fluoro substituents provide reactive sites for further chemical modifications, enabling the exploration of diverse derivatives with potential biological activity.
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