1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
97%
- Product Code: 121021
CAS:
154093-72-8
| Molecular Weight: | 281.21 g./mol | Molecular Formula: | C₁₃H₉F₂NO₄ |
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| EC Number: | MDL Number: | MFCD25973506 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry and sealed |
Product Description:
This compound is primarily utilized in the development of antibacterial agents, particularly fluoroquinolone antibiotics. It serves as a key intermediate in the synthesis of drugs that target bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication. The structural features of this compound, including the cyclopropyl and difluoro groups, enhance its ability to penetrate bacterial cells and improve its binding affinity to target enzymes. Its application is significant in creating broad-spectrum antibiotics effective against both Gram-positive and Gram-negative bacteria, making it valuable in treating respiratory, urinary tract, and gastrointestinal infections. Additionally, its role in combating antibiotic-resistant strains of bacteria highlights its importance in modern medicinal chemistry.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿2,385.00 |
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| 1.000 | 10-20 days | ฿4,761.00 |
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| 5.000 | 10-20 days | ฿14,049.00 |
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1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
This compound is primarily utilized in the development of antibacterial agents, particularly fluoroquinolone antibiotics. It serves as a key intermediate in the synthesis of drugs that target bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication. The structural features of this compound, including the cyclopropyl and difluoro groups, enhance its ability to penetrate bacterial cells and improve its binding affinity to target enzymes. Its application is significant in creating broad-spectrum antibiotics effective against both Gram-positive and Gram-negative bacteria, making it valuable in treating respiratory, urinary tract, and gastrointestinal infections. Additionally, its role in combating antibiotic-resistant strains of bacteria highlights its importance in modern medicinal chemistry.
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