THP-PEG4-Pyrrolidine(N-Me)-CH2OH
95%
- Product Code: 121683
CAS:
2378261-81-3
| Molecular Weight: | 391.50 g./mol | Molecular Formula: | C₁₉H₃₇NO₇ |
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| Density: | Storage Condition: | -20°C |
Product Description:
This compound is primarily utilized in the field of bioconjugation and drug delivery due to its unique structure. The THP (tetrahydropyran) group acts as a protective moiety, ensuring stability during chemical reactions, while the PEG4 (polyethylene glycol) spacer enhances solubility and reduces immunogenicity. The pyrrolidine ring, with its N-methyl substitution, contributes to improved pharmacokinetic properties by increasing metabolic stability. The hydroxymethyl group (-CH2OH) serves as a reactive site for further functionalization, enabling the attachment of targeting ligands or therapeutic agents. This makes it a versatile building block in the synthesis of prodrugs, antibody-drug conjugates, and other targeted delivery systems, particularly in oncology and immunotherapy. Its design allows for controlled release and targeted action, minimizing off-target effects and improving therapeutic efficacy.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿44,010.00 |
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THP-PEG4-Pyrrolidine(N-Me)-CH2OH
This compound is primarily utilized in the field of bioconjugation and drug delivery due to its unique structure. The THP (tetrahydropyran) group acts as a protective moiety, ensuring stability during chemical reactions, while the PEG4 (polyethylene glycol) spacer enhances solubility and reduces immunogenicity. The pyrrolidine ring, with its N-methyl substitution, contributes to improved pharmacokinetic properties by increasing metabolic stability. The hydroxymethyl group (-CH2OH) serves as a reactive site for further functionalization, enabling the attachment of targeting ligands or therapeutic agents. This makes it a versatile building block in the synthesis of prodrugs, antibody-drug conjugates, and other targeted delivery systems, particularly in oncology and immunotherapy. Its design allows for controlled release and targeted action, minimizing off-target effects and improving therapeutic efficacy.
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