tert-Butyl 4-((1R,2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)piperidine-1-carboxylate
98%
- Product Code: 124255
CAS:
1174020-63-3
| Molecular Weight: | 458.55 g./mol | Molecular Formula: | C₂₄H₃₄N₄O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 665.9±55.0 °C(Predicted) | |
| Density: | 1.27±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
This compound is primarily utilized in pharmaceutical research and development, particularly in the synthesis of beta-lactamase inhibitors. These inhibitors play a critical role in combating antibiotic resistance by preventing the breakdown of beta-lactam antibiotics, such as penicillins and cephalosporins, by bacterial enzymes. The compound’s structure, featuring a diazabicyclooctane core, is key to its activity, as it mimics the transition state of the enzyme-substrate interaction, effectively blocking the enzyme’s function. Its application extends to the development of combination therapies, where it is paired with beta-lactam antibiotics to enhance their efficacy against resistant bacterial strains. Additionally, it serves as an intermediate in the production of more complex molecules designed to address multidrug-resistant infections.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Colourless To White To Orange Solid |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿46,800.00 |
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| 0.050 | 10-20 days | ฿98,000.00 |
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tert-Butyl 4-((1R,2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)piperidine-1-carboxylate
This compound is primarily utilized in pharmaceutical research and development, particularly in the synthesis of beta-lactamase inhibitors. These inhibitors play a critical role in combating antibiotic resistance by preventing the breakdown of beta-lactam antibiotics, such as penicillins and cephalosporins, by bacterial enzymes. The compound’s structure, featuring a diazabicyclooctane core, is key to its activity, as it mimics the transition state of the enzyme-substrate interaction, effectively blocking the enzyme’s function. Its application extends to the development of combination therapies, where it is paired with beta-lactam antibiotics to enhance their efficacy against resistant bacterial strains. Additionally, it serves as an intermediate in the production of more complex molecules designed to address multidrug-resistant infections.
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