(3R,5R,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
≥98%
- Product Code: 124645
CAS:
1094100-06-7
| Molecular Weight: | 481.54 g./mol | Molecular Formula: | C₂₂H₂₈FN₃O₆S |
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| Density: | Storage Condition: | 2-8°C, dry, sealed |
Product Description:
This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of statin drugs, which are widely prescribed for managing cholesterol levels. Its structure is crucial for inhibiting HMG-CoA reductase, an enzyme involved in cholesterol production in the liver. By blocking this enzyme, it helps reduce LDL cholesterol and triglycerides while increasing HDL cholesterol, thereby lowering the risk of cardiovascular diseases. Additionally, its specific stereochemistry and functional groups make it a key component in developing more potent and selective statin derivatives for improved therapeutic efficacy and reduced side effects.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | £685.16 |
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(3R,5R,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of statin drugs, which are widely prescribed for managing cholesterol levels. Its structure is crucial for inhibiting HMG-CoA reductase, an enzyme involved in cholesterol production in the liver. By blocking this enzyme, it helps reduce LDL cholesterol and triglycerides while increasing HDL cholesterol, thereby lowering the risk of cardiovascular diseases. Additionally, its specific stereochemistry and functional groups make it a key component in developing more potent and selective statin derivatives for improved therapeutic efficacy and reduced side effects.
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