ABC-294640

98%

  • Product Code: 124660
  CAS:    915385-81-8
Molecular Weight: 380.91 g./mol Molecular Formula: C₂₃H₂₅ClN₂O
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: ABC-294640 is primarily investigated for its potential therapeutic applications, particularly in the field of oncology. It functions as a selective sphingosine kinase 2 (SphK2) inhibitor, which plays a role in regulating cell growth, survival, and inflammation. By inhibiting SphK2, ABC-294640 has shown promise in reducing tumor growth and inducing apoptosis in various cancer models, including breast, prostate, and liver cancers. Additionally, it is being studied for its anti-inflammatory properties, which could be beneficial in treating conditions like rheumatoid arthritis and inflammatory bowel disease. Research also explores its potential in managing fibrosis and other diseases linked to abnormal cell proliferation and inflammation. Its ability to modulate sphingolipid metabolism makes it a compound of interest in both cancer therapy and inflammatory disorders.
Product Specification:
Test Specification
Appearance Solid
Purity (%) 97.5-100
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.001 10-20 days ฿2,260.00
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-
0.005 10-20 days ฿5,610.00
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-
0.025 10-20 days ฿10,990.00
+
-
0.050 10-20 days ฿15,380.00
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-
ABC-294640
ABC-294640 is primarily investigated for its potential therapeutic applications, particularly in the field of oncology. It functions as a selective sphingosine kinase 2 (SphK2) inhibitor, which plays a role in regulating cell growth, survival, and inflammation. By inhibiting SphK2, ABC-294640 has shown promise in reducing tumor growth and inducing apoptosis in various cancer models, including breast, prostate, and liver cancers. Additionally, it is being studied for its anti-inflammatory properties, which could be beneficial in treating conditions like rheumatoid arthritis and inflammatory bowel disease. Research also explores its potential in managing fibrosis and other diseases linked to abnormal cell proliferation and inflammation. Its ability to modulate sphingolipid metabolism makes it a compound of interest in both cancer therapy and inflammatory disorders.
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