BMS-345541
98%
- Product Code: 124696
CAS:
445430-58-0
| Molecular Weight: | 255.32 g./mol | Molecular Formula: | C₁₄H₁₇N₅ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | -20℃ |
Product Description:
BMS-345541 is primarily used in biochemical research as a selective inhibitor of the IκB kinase (IKK) complex, particularly targeting IKKβ. This compound is valuable in studying the NF-κB signaling pathway, which plays a critical role in inflammation, immune response, and cell survival. Researchers utilize BMS-345541 to investigate the effects of inhibiting this pathway in various disease models, such as cancer, autoimmune disorders, and chronic inflammatory conditions. Its ability to modulate NF-κB activity makes it a useful tool for understanding the molecular mechanisms underlying these diseases and for exploring potential therapeutic strategies. Additionally, BMS-345541 is employed in cell culture studies to assess its impact on gene expression, cytokine production, and apoptosis, providing insights into cellular responses to IKK inhibition.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿2,772.00 |
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| 0.005 | 10-20 days | ฿6,930.00 |
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| 0.025 | 10-20 days | ฿22,239.00 |
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BMS-345541
BMS-345541 is primarily used in biochemical research as a selective inhibitor of the IκB kinase (IKK) complex, particularly targeting IKKβ. This compound is valuable in studying the NF-κB signaling pathway, which plays a critical role in inflammation, immune response, and cell survival. Researchers utilize BMS-345541 to investigate the effects of inhibiting this pathway in various disease models, such as cancer, autoimmune disorders, and chronic inflammatory conditions. Its ability to modulate NF-κB activity makes it a useful tool for understanding the molecular mechanisms underlying these diseases and for exploring potential therapeutic strategies. Additionally, BMS-345541 is employed in cell culture studies to assess its impact on gene expression, cytokine production, and apoptosis, providing insights into cellular responses to IKK inhibition.
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