Boc-L-Trp(For)-OH
97%
- Product Code: 126629
Alias:
N-tert-butoxycarbonyl-N'-formyl-L-tryptophan
CAS:
47355-10-2
| Molecular Weight: | 332.35 g./mol | Molecular Formula: | C₁₇H₂₀N₂O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00065992 | |
| Melting Point: | ~100 °C (dec.) | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
This compound is primarily used in peptide synthesis as a protected form of tryptophan. The Boc (tert-butoxycarbonyl) group safeguards the amino group, while the formyl (For) group protects the indole side chain of tryptophan. This dual protection allows for selective reactions during the synthesis of complex peptides, ensuring that the tryptophan residue remains intact and unaltered. It is particularly valuable in solid-phase peptide synthesis (SPPS) and other methodologies where precise control over amino acid reactivity is essential. Additionally, it finds application in the preparation of peptide-based pharmaceuticals, research peptides, and bioactive compounds, where protecting groups are crucial for achieving high yields and purity.
Product Specification:
| Test | Specification |
|---|---|
| Melting Point | 132-134 |
| Purity (HPLC) | 97-100 |
| Purity (Nonaqueous Titration) | 98-100 |
| Specific Rotation [A]20/D(C=2, Ethanol) | 17-21 |
| Appearance | White To Light Yellow Powder |
| Infrared Spectrum | Conforms To Structure |
| TLC Analysis | One Spot |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿680.00 |
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| 5.000 | 10-20 days | ฿1,490.00 |
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| 25.000 | 10-20 days | ฿5,770.00 |
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Boc-L-Trp(For)-OH
This compound is primarily used in peptide synthesis as a protected form of tryptophan. The Boc (tert-butoxycarbonyl) group safeguards the amino group, while the formyl (For) group protects the indole side chain of tryptophan. This dual protection allows for selective reactions during the synthesis of complex peptides, ensuring that the tryptophan residue remains intact and unaltered. It is particularly valuable in solid-phase peptide synthesis (SPPS) and other methodologies where precise control over amino acid reactivity is essential. Additionally, it finds application in the preparation of peptide-based pharmaceuticals, research peptides, and bioactive compounds, where protecting groups are crucial for achieving high yields and purity.
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