2'-Deoxy-2'-fluorouridine
98.0%
- Product Code: 126923
Alias:
2'-Fluoro-2'-deoxyuridine
CAS:
784-71-4
| Molecular Weight: | 246.19 g./mol | Molecular Formula: | C₉H₁₁FN₂O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD01317293 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | room temperature |
Product Description:
Used primarily in the development of antiviral drugs, particularly for treating RNA virus infections. It serves as a nucleoside analog that inhibits viral replication by incorporating into viral RNA, causing chain termination. This mechanism is crucial in the treatment of diseases caused by viruses like hepatitis C and certain respiratory viruses. Additionally, it is researched for its potential in cancer therapy, where it can disrupt the synthesis of DNA in rapidly dividing cancer cells. Its fluorinated structure enhances its stability and bioavailability, making it a valuable component in medicinal chemistry.
Product Specification:
| Test | Specification |
|---|---|
| Melting Point | 147-153 |
| Purity (HPLC) | 97.5-100 |
| Purity (Neutralization Titration) | 95-100 |
| Specific Rotation [A]20/D(C=0.3, H2O) | 50-56 |
| Appearance | White To Off-White Powder Or Crystals |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $38.98 |
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| 5.000 | 10-20 days | $149.82 |
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2'-Deoxy-2'-fluorouridine
Used primarily in the development of antiviral drugs, particularly for treating RNA virus infections. It serves as a nucleoside analog that inhibits viral replication by incorporating into viral RNA, causing chain termination. This mechanism is crucial in the treatment of diseases caused by viruses like hepatitis C and certain respiratory viruses. Additionally, it is researched for its potential in cancer therapy, where it can disrupt the synthesis of DNA in rapidly dividing cancer cells. Its fluorinated structure enhances its stability and bioavailability, making it a valuable component in medicinal chemistry.
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