DM4

≥98%

  • Product Code: 126985
  Alias:    Maytansine DM4; N2'-Deacetyl-N2'-(4-Mercapto-4-methyl-1-oxopentyl)-Maytansine
  CAS:    796073-69-3
Molecular Weight: 780.37 g./mol Molecular Formula: C₃₈H₅₄ClN₃O₁₀S
EC Number: MDL Number: MFCD28144516
Melting Point: 185-187 °C (decomp) Boiling Point: 943.2±65.0 °C
Density: 1.29±0.1 g/cm3 Storage Condition: 2-8°C, dry, sealed
Product Description: DM4 is primarily utilized in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It functions as a potent cytotoxic agent that is linked to monoclonal antibodies, which specifically bind to antigens on cancer cells. Once the ADC is internalized by the cancer cell, DM4 is released, disrupting microtubule function and leading to cell death. This approach minimizes damage to healthy tissues, making it a valuable component in precision medicine for treating various cancers, including breast, lung, and lymphoma. Its high potency and targeted delivery enhance the efficacy of cancer treatments while reducing systemic toxicity.
Product Specification:
Test Specification
Appearance White To Light Yellow Powder
Purity (%) 97.5-100
Infrared Spectrum Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.001 10-20 days €73.87
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-
0.005 10-20 days €226.89
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0.025 10-20 days €787.77
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DM4
DM4 is primarily utilized in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It functions as a potent cytotoxic agent that is linked to monoclonal antibodies, which specifically bind to antigens on cancer cells. Once the ADC is internalized by the cancer cell, DM4 is released, disrupting microtubule function and leading to cell death. This approach minimizes damage to healthy tissues, making it a valuable component in precision medicine for treating various cancers, including breast, lung, and lymphoma. Its high potency and targeted delivery enhance the efficacy of cancer treatments while reducing systemic toxicity.
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